101 Dalmatians is a family comedy film. Roger Dearly is a video programmer that lives with his dalmatian Pongo. One day he takes Pongo out for a walk in the park, and Pongo is interested in a female dalmatian Perdy. Roger and Pongo are off on a chase through out the streets and discovers that Perdy liked Pongo. In through the walk in the park Roger meets Anita Campbell-Green who is Perdy's owner the two fall in love and all four of them are one big happy family.
Anita Campbell-Green is a fashion designer. Anita works at House of de Vil and the posh Cruella de Vil is her boss. Cruella de Vil must have her cigarettes and her furs. Inspired by her dalmatians Anita designs a spotted fur coat. Her boss is delighted and thinks of the concept of making coats out of real dalmatians. She offers Anita and Roger a lot of money when she discovers that Perdy has given birth to 15 puppies but they refuse the offer.
Cruella de Vil lets Anita go and she is determined to seek revenge out on both she and Roger. Jasper and Horace who are Cruella's go to men steal the puppies and bring them to Cruella's mansion. The other animals are aware that the puppies are stolen and they out smart Jasper and Horace and the puppies wait at the farm for their parents.
Cruella does not give up and arrives at the farm in an attempt to get the puppies, but she is kicked into mud and is covered in molasses by a horse. Eventually all of the puppies are recovered by the Metropolitan Police Service and are sent back home safe and sound. Cruella, Jasper, and Horace are arrested. Roger and Anita are compelled to adopt all of the dalmatians that Cruella and her gang stole and thus brings the total to 101 dalmatians.