Great Falls natives Erik and Cooze (Mike Coozeman) are now freshmen at the University of Michigan, and a group of fraternity geeks try to spoil their fun. However, the Betas do not stop short of fighting for their right to party as long as they want. In fact, this is the promise of this wildest fraternity on campus-girls everywhere and non-stop entertainment.
Along with Erik and Cooze, their best friend Bobby joins the Beta pledges. Together the three of them become determined to enjoy college life to its fullest. However, they are met with great opposition. The petition for fun continues as the Beta House becomes pressured by the new GEK ("Geek") house to set new standards regarding partying and outrageous behavior.
Leader of this new nerd clan of strives for supremacy, but they are not met with compliance by the Betas. Despite the GEK house's best effort, the debauchery, pranks, parties, and craziness continues. It seems almost hopeless for the Geeks to try to stop it.
In the midst of all this contention, Erik meets Ashley, and that helps heal his heart from a high school break-up taking place less than a year prior. Cooze attempts to date Ashley's roommate Denise, but that situation becomes more complicated than anticipated.
Romantic drama ensues while the battle for number one carries on. Finally, everyone agrees that the only way to settle the rivalry is to re-start an ancient Greek gaming tradition banned 40 years ago. One question remains throughout each match. That is, who is the really bully-the Geeks or the Betas?
Truth eventually becomes evident, but it takes quite a bit of embarrassment and torture for that truth to finally surface. For one, a total of 50 tasks by new Beta pledges are required to be completed by semester's end in order for them to become a true Beta. However, it seems as if peer pressure is not the only reason for this craving of acceptance amongst this group of new boys.
Overtones of family dysfunction show itself in several scenes of American Pie Presents: Beta House. The most obvious of such is the beginning scene during which a father shows his son a list of women he's "done" in his lifetime. Right or wrong, he encourages his son to "keep up with his old man." However, in spite of family issues, each new college boy proceeds onto finding his own way.