Odd Girl Odd is a made for television movie that takes a look into the secret world of girls bullying one other in high school. It also focuses on the drama and damage that girls can do to one another just to be part of the crowd. Vanessa Snyder(Alexa Vega) has it all, she is beautiful, has a very supportive mother, Barbara(Lisa Vidal), lots of friends, and does well in school. She is part of the popular group along with her friends Stacy Larson(Leah Pipes) and Nikki Rodriguez(Elizabeth Rice). Then there are girls like Emily and Tiffany that are on the outside of the clique that would do anything to be in.
Unfortunately there are some jealousy issues with Nikki and the rest of the girls. Nikki tries to cause contentions with Vanessa and Stacy's friendship by scheming Vanessa into getting to know Stacy's crush. Stacy is devastated when she finds out what Vanessa did and the bullying begins. Soon Vanessa is kicked out of the group and soon ostracized by everyone. Nikki then invites Tiffany into the group because she was willing to do anything.
The bullying continues to escalate until the point that Vanessa withdrawals from everything in school. She chops off her hair and attempts to take her life by swallowing her mother's sleeping medication. Around this time Vanessa becomes friends with Emily who encourages her not to give into the rumors and pettiness that the former friends were spreading.
Barbara seeing all this bullying is desperate to stop it, takes all the statements to the school. She is told that since the no one has physically touched Vanessa, there is nothing that they can do. Vanessa returns back to school from the hospital. Stacy pretends she wants to be friends again over instant messages. Graduation day arrives and Vanessa finds out the truth when Nikki and Tiffany begin to read the conversation that happened, making Vanessa realize it was all a setup. Instead of running away, Vanessa stands up for herself and the bullying stops.