Ten years have passed and Sidney Prescott (Neve Campbell) returns back to Woodsboro, this time with her own agenda, to celebrate the last stop of her tour for her recently written self-help book written about her personal experiences surviving the "Woodsboro Massacre". The whole Scream "team" is back in this episode, including Dewey (David Arquette) and reporter Gail Weathers (Courteney Cox) who is now married to Dewey. We also meet Sidney's cousin Jill (Emma Roberts) and Aunt Kate (Mary McDonnell). Sidney's return to Woodsboro also perpetuates the return of the malevolent Ghostface.
Keeping true to the other movies in the Scream saga, Scream 4 begins with the vicious killings of two high school girls. Welcoming Sidney back to town, the killings of the two girls are mysteriously linked to a phone found in Sidney's rental car.
Staying at her Aunt Kate and Cousin Jill's home, Sidney begins to see a lot of herself in Jill's life, especially when she witnesses Jill's ex-boyfriend sneaking in to see Jill through Jill's window. While watching a movie, Jill and best friend Kirby receive a phone call from ghostface claiming to be in the closet, Kirby checks the closet to find it empty. The girls then realize that ghostface in the closet of the girl (Olivia) next door, as they witness her brutal murder. As Sidney hears the girls screaming, she rushes next door to intervene, only to arrive too late.
As the original three (Sidney, Dewey, and Gale) search for answers, Gale finds herself at a "Stab-a-thon" party, where she is attacked and stabbed by Ghostface while viewing the party via webcam in her van. Gale is rushed to the hospital, where she survives her injuries.
With numerous other stabbings, twists, and turns, the viewers are then taken to get-together at Kirby's house. Sidney arrives looking for Jill. By process of elimination, the viewers are led to believe that Charlie (Rory Culkin), member of the High School Cinema Club is Ghostface. This theory seems compelling until Sidney escapes an attack by Charlie and heads toward the front door, and is stabbed by Ghostface. As Ghostface removes his mark, the viewers will learn that Ghostface is Jill, Sidney's cousin. Ranting about an undying hatred for her cousin, Jill explains that it is now her turn for fame. After shooting Charlie and ex-boyfriend, Trevor, Jill turns the gun on Sidney, supposedly killing her.
Jill then sets the scene to make it appear that her ex-boyfriend was Ghostface, mirroring Sidney's original experience. Upon Dewey and the other officers arrival, Jill is labeled a "survivor".
In the hospital, Jill learns that Sidney survived. Jill sneaks into Sidney's room, desiring to kill her cousin. After a struggle with Dewey's gun, Sidney shocks Jill with the defibrillator.
While, the viewers are relieved as it seems that Ghostface is finally gone, they should be prepared for one final scare.
Few bonus materials get as interesting as when releases include alternate or extended opening or extended sequences. With "Scream 4" hitting DVD and Blu-Ray Oct. 4, fans can check out an alternate take on the film's opening scene that changes up a few early kills. Check out the different openings here.
Horror writer, director and legend Wes Craven sat down recently with IGN.com on the cusp of "Scream 4" hitting Blu-Ray and DVD Oct. 4th, and talked about what the future may hold for "Scream 5," including his possible involvement as a director.