Watch Desperately Seeking Susan

Rosanna Arquette plays a New Jersey housewife name Roberta who is bored with her life. Her husband doesn't excite her and she spends every day doing the same mundane household tasks. But her life begins to change when she spots the first of a series of personal ads in the newspaper in which someone is "Desperately Seeking Susan." Roberta becomes fascinated by the ads and decides to go into New York City and try and find the mysterious Susan (played by Madonna). When an ad suggests that Susan meet the man in Battery Park, Roberta also shows up and through a series of misunderstandings finds herself on the run from both Susan and some men who are searching for some stolen Egyptian jewelry.

At one point Roberta gets amnesia and there is a series of escalating misunderstandings that at one point involve Susan becoming involved with Roberta's husband (played by Aiden Quinn).