Watch Barbara Bush: First Mom

The remarkable life of the first woman since Abigail Adams to be wife to one U.S. President and mother to another. Our profile includes some lesser-known details of Mrs. Bush's life, including: the death of her 3-year-old daughter from leukemia; the depression she suffered in the mid-1970s; and her battles with Nancy Reagan when Barbara felt she and husband George had been given short shrift when he was V.P. We also cover her long crusade against illiteracy and her enormous popularity as First Lady.