This is a horror movie that takes place in New York City. The city is hit with an unknown virus, that some believe has started with rats. It affects people that are bitten by rats, these people are transformed into rat like creatures. The plot centers around six tenants of a run down apartment building on Mulberry Street. The tenants are grappling with tenant related issues like not enough heat when the virus strikes, the plot thickens as the tenants struggle to fend off the rats and the rat like creatures. There are many unexpected twists and turns in this story.