This horror comedy is the latest installment of the franchise that began in the 1990s. This film functions as both a reboot and a sequel as it brings back original stars and introduces a new cast. Twenty-five years after Billy Loomis and Stu Macher terrorized the town of Woodsboro, a high school student named Tara Carpenter is home alone when she is attacked by Ghostface and left hospitalized. Out of town, Tara's estranged older sister Sam Carpenter is informed by Wes Hicks, one of Tara's friends, about her sister's attack. Sam returns to Woodsboro with her boyfriend Richie to visit Tara at the hospital where Sam is reunited with Tara's friend group; Wes, Amber Freeman, twins Chad and Mindy Meeks-Martin, and Liv McKenzie. Liv's summer fling Vince Schneider, who is later revealed to be Stu Macher's nephew, is next to be killed by Ghostface. After Sam's arrival at the hospital, she is attacked by Ghostface, and tells her sister Tara that she's been dealing with hallucinations of Billy Loomis. Sam then tells Tara that Billy is her biological father after discovering the truth years prior, which resulted in their parents separation and why Sam became estranged from her. The next day, Sam and Richie pay Dewey Riley a visit, who has been depressed since his divorce from Gale Weathers. The pair ask for his help in stopping the killer, and he later contacts Sidney Prescott and Gale, warning them about the return of Ghostface. Dewey then joining the teens at Mindy and Chad's home, and is reunited with the twins' mother Martha, the sister of the late Randy Meeks. With the three attacks being on people related in some capacity to the original killers, Sam is accused of being the killer.