Ep 1. Antonio Banderas, Charlyne Yi, Ed Gamble

In the premiere episode of season 6 of Conan, host Conan O'Brien welcomes three guests: Antonio Banderas, Charlyne Yi, and Ed Gamble. Banderas, the famous Spanish actor and director, joins Conan to discuss his upcoming film, "The Hitman's Wife's Bodyguard," in which he stars alongside Ryan Reynolds and Samuel L. Jackson. Banderas shares stories of his experience working with the two comedic actors, and discusses his approach to playing villains on screen. As always, Conan is quick to point out Banderas' impressive career and his enduring status as a Hollywood heartthrob.

Next up is comedian Charlyne Yi, who has appeared in films like "Knocked Up" and "This Is 40," as well as the television series "House." Yi discusses her new series, "Tig n' Seek," which is a children's show that she created and stars in. The show centers around a young girl named Tig who, with the help of her cat, solves mysteries around the city. Yi talks about the challenges of creating a show for young audiences that is also appealing to adults, and shares some of her favorite moments from the set.

Finally, British comedian Ed Gamble takes the stage to discuss his new comedy special, "Blood Sugar," which was filmed during the pandemic. Gamble talks about the difficulties of performing comedy without a live audience, and shares some behind-the-scenes stories from the filming process. He also discusses his love of food and cooking, and how he's been coping with being a comedian during a time when live performances are limited.

Throughout the episode, Conan keeps the energy high with his trademark wit and humor, cracking jokes with his guests and engaging in off-the-cuff banter. Viewers are sure to be entertained by the lively back-and-forth between Conan and his guests, as they cover a wide range of topics and share their unique perspectives on the world of entertainment.