Ep 1. Matthew Shepard's Parents, Leeza Gibbons & The Browns from "Sister Wives"

In the season 4 premiere of Oprah: Where Are They Now?, viewers get an in-depth look at the lives of three families who have faced significant challenges. The first family featured is the parents of Matthew Shepard, the 21-year-old college student who was brutally beaten and left to die in a hate crime in 1998. Matthew's parents, Judy and Dennis, discuss their ongoing work to promote LGBTQ rights and ensure that hate crimes are properly prosecuted. They also share their memories of Matthew and how they have coped with the loss of their son.

Next, viewers catch up with talk show host and journalist Leeza Gibbons. Leeza opens up about her mother's battle with Alzheimer's disease and how it inspired her to create the Leeza Gibbons Memory Foundation, which supports those affected by memory disorders. She also discusses her work as a caregiver and how she balances her personal and professional life.

Finally, the show checks in with the Brown family, stars of the reality series "Sister Wives." Kody, Janelle, Meri, Christine, and Robyn Brown share their thoughts on plural marriage and how their unconventional lifestyle has impacted their children. They also discuss the challenges they face as a family, including legal issues and societal stigmas.

Overall, episode 1 of Oprah: Where Are They Now? season 4 provides viewers with inspiring stories of resilience, compassion, and perseverance in the face of adversity.