Charlie Rose Season 5 Episode 29 Charlie Rose - Charlie Rose Brain Series 2: Depression (May 29, 2012)

In the 29th episode of the fifth season of Charlie Rose, the host continued his series on the human brain with a focus on depression. The episode featured interviews with four experts in the field of mental health: Dr. Richard Friedman, a professor of psychiatry at Weill Cornell Medical College; Dr. Julio Licinio, a professor of translational medicine and psychiatry at the University of Miami; Dr. Helen Mayberg, a professor of psychiatry, neurology, and radiology at Emory University; and Dr. Eric Nestler, a professor of psychiatry and neuroscience at Mount Sinai Medical Center.

Throughout the episode, Rose and his guests discussed the various aspects of depression, including its causes, symptoms, and potential treatments. The conversation also delved into the stigma surrounding mental health issues and the importance of seeking help when struggling with depression.

Dr. Friedman, who has extensively researched the use of medication in treating depression, explained that while antidepressants can be effective for some patients, they are not a one-size-fits-all solution. He emphasized the importance of personalized treatment plans, which may include medication, therapy, lifestyle changes, or a combination of these approaches.

Dr. Licinio spoke about the role of genetics in depression. He explained that while there is not a single "depression gene," there are likely many genetic factors that can contribute to the development of the condition. He also discussed the potential for using genetic testing to identify individuals who may be at a higher risk for depression.

Dr. Mayberg, who has done groundbreaking research on using deep brain stimulation to treat depression, explained how this approach works and the potential benefits it may offer for individuals who have not found relief from other treatments. She also emphasized the need for personalized treatment plans that take into account each individual's unique symptoms and needs.

Finally, Dr. Nestler discussed the neurobiological underpinnings of depression and the potential for new treatments that target specific brain circuits. He also spoke about the importance of addressing underlying factors such as stress and trauma that can contribute to the development of depression.

Throughout the episode, Rose and his guests underscored the importance of seeking help for depression and the need for continued research and innovation in the field of mental health. They also emphasized that depression is a treatable condition and that recovery is possible with the right approach.

Overall, the 29th episode of the fifth season of Charlie Rose provided a valuable and informative discussion of depression and its potential treatments. This episode should be of interest to anyone who has been affected by depression, as well as to mental health professionals, researchers, and others who are interested in learning more about this complex and challenging condition.