Ep 2. Ghost in Your Genes

NOVA season 35 episode 2, Ghost in Your Genes, is a fascinating exploration into the world of epigenetics. Through interviews with leading scientists in the field and real-life stories of individuals impacted by epigenetic changes, this episode delves into how our genes can be altered by factors beyond just our DNA sequence.

The episode first introduces us to the concept of epigenetics, explaining that it is the study of changes in gene expression that occur without alterations to the underlying DNA sequence. These changes can occur due to environmental factors, such as toxins or stress, as well as during development in the womb. The episode points out that these epigenetic changes can be inherited, meaning they can be passed down from one generation to the next.

The program then goes on to showcase a number of real-life examples of epigenetic changes. It introduces us to individuals who were born small and grew up to have health problems as adults. Through studies of these people, scientists have discovered that the conditions in the womb can have a profound impact on our long-term health. Similarly, the episode also looks at the effects of stress on the body and how it can increase the risk of certain diseases.

Perhaps the most fascinating part of the episode is its exploration of how epigenetic changes can be inherited. The show introduces us to a pair of identical twins who are genetically identical, yet look and behave very differently. It is discovered that these differences are due to epigenetic changes that occurred in one twin but not the other. These epigenetic changes were then passed down to the twin's children, resulting in further differences between the two families.

The episode also looks at epigenetic changes that can occur due to exposure to toxins. Through studies of rats exposed to a specific chemical, scientists have discovered that the effects of the toxin can be passed down to future generations. This has implications for humans as well, as exposure to toxins in the environment can have long-lasting impacts on our health and the health of our offspring.

Throughout the show, we hear from a number of leading epigenetics researchers who explain the science behind these fascinating discoveries. They discuss the ways in which epigenetics is changing our understanding of genetics and even the concept of inheritance itself.

Overall, Ghost in Your Genes is a thought-provoking exploration of a fascinating and fast-evolving field of science. It will make you think twice about the factors that impact our genes and the long-lasting effects they can have on our health and the health of our descendants.