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Swamp Thing (1982) is a horror/adventure film directed by Wes Craven. The film is set in the swamps of Louisiana. The beginning of the film depicts Dr. Alec Holland working with his sister, Linda, on a top secret project. The project involves developing a bioengineering formula that can create a hybrid plant and animal organism that can survive in any type of environment.

A government agent by the name of Alice Cable arrives at the lab where Holland works. She looks to oversee the experiment in some way and begins to develop feelings for Holland. Holland remains distracted because he is about to make a major breakthrough with the serum he is creating.

The plot of the film takes a twist when the evil mad scientist, Dr. Anton Arcane arrives on the scene with a paramilitary group. Arcane has become obsessed with the notion of becoming an immortal and believes that what Holland is creating in the lab could very well lead him to his long sought after goal.

The group attacks the lab and ends up killing Linda. In the melee, Holland is bathed in the bioengineering formula and set afire. He runs out of the lab and jumps into the waters of the swamp. The organic matter of the swamp. mixes with Holland's flesh and the chemicals. This turns him into the half man/half plant creature known as the Swamp Thing. Given enhanced powers as a result, the Swamp Thing lays siege on the forces of Anton Arcane.

Arcane eventually develops his own version of the formula and turns himself into a more feral version of the Swamp Thing. In the climax of the film, the two creatures meet in a final battle to the death.