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The mayor proves that a serum based on Michiru's blood cures Nirvasyl Syndrome, but Alan moves forward with his plan to "solve" the beastman problem.

While Barbaray escapes from her captivity and heads back to Anima-City with Pinga's help, Marie informs Shirou that Nazuna is planned to reveal that she is a human, which Nazuna is told is supposed to calm the beastkin. As the concert gets underway, Shirou informs Michiru thats Nazuna's confession will actually trigger the Nirvasyl Syndrome. Michiru convinces Nazuna not to make the confession, only for Cliff to expose her himself which, along with weapons sent in by Alan, sets off the syndrome in several beastkin. Shocked by this, Shirou also succumbs to the syndrome and attacks Michiru.

Upon encountering another berserk beastkin, Michiru and Shirou attempt to take it down when a group of drones called Engel Machines appear and capture it. Following the trail to the medical center, they find that the drones were sent by Alan, who claims that the so-called "Nirvasyl Syndrome" is the result of stress caused by several species of beastkin amassing together and is what wiped out Shirou's village. When Alan reveals he intends to prevent this by developing a vaccine to turn beastkin into regular humans, Shirou becomes furious at the idea, going against both Michiru and the police. While Alan tasks Michiru and Nazuna with putting on a concert to calm the beastkin until the vaccine is complete, Barbaray tells Shirou she is planning on dismantling Anima-City to disperse the beastkin to keep them safe. However, when Barbaray goes to visit Minister Shiramizu regarding the matter, he places her under arrest, as it is revealed he is working alongside Alan.

Upon seeing Nazuna being allegedly abducted, Michiru breaks into the medical center to rescue her, only to discover she is there for an MRI scan. Alan then tells Michiru that she and Nazuna became beastkin as a result of a blood transfusion mishap and he is working with Nazuna to develop a cure.

Following Alan's rescue, support for the Silver Wolf cult increases, leading to their refuge being approved. Just as Shirou and Michiru go to visit the prison to find out the assassin's motives, Yaba, one of the doctors that Shirou stopped before, goes berserk following a visit from Silver Wolf priest Cliff Boris. As both Shirou and Michiru struggle against the powered up Yaba, Shirou is forced to reveal his true identity as the legendary wolf Ginrou in order to defeat him. While Shirou recovers, Barbaray explains to Michiru how Shirou became Ginrou over a thousand years ago, when the beastkin of Nirvasyl were allegedly wiped out by humans.

Michiru meets a albatross beastkin named Pinga, whose species has faced trouble migrating to the beastkin restrictions placed on them. Meanwhile, Barbaray and Shirou have an encounter with Alan Sylvasta, head of Sylvasta Pharmaceuticals, who advises against giving the Silver Wolf cult refuge. After Pingu flies Michiru across the city, Shirou suspects that Pingu may be a terrorist. Spotting Pingu approach the Mayor's office, Shirou stops him with the help of Michiru's new flight ability, finding his planned terrorism was a bluff and deciding to let him go. Meanwhile, Alan is attacked by a hitman but is rescued by Nazuna.

Michiru discovers that Nazuna Hiwatashi, her best friend who caught the beastkin disease before she did, has joined a cult dedicated to the mythology of a silver wolf. Wanting to help cure Nazuna's condition too, Michiru arranges for Nazuna to meet with Barbaray. However, Nazuna takes advantage of the situation to secure a settlement for her cult, stating that she prefers being the cult's idol and leaving Michiru downhearted.

While watching a deadly baseball game, Michiru's powers catch the attention of the Bears team, helping them win their match as their pitcher. Enjoying the feeling, Michiru continues to play with them, unaware that their coach has been gambling on them losing. During a finals match, where the team is being bribed to lose, an incident in which the coach attempts to steal all the gambled money for himself leads to the crowd going wild. As Shirou resolves this matter, Michiru shows the importance of what baseball truly means, and despite the Bears ultimately losing, they appreciate playing fair and square.

Michiru meets Nina, the dolphin beastkin daughter of a gang boss, who has posting to social media in human form. Managing to regain the ability to turn into human form, Michiru joins Nina as she attends a human party, which initially seems to accept Nina even after she accidentally reveals herself as a beastkin. During the party however, one of the girls puts Nina into a fishtank without realizing she can't actually breathe, forcing Michiru to use her transformation powers to save her. Despite the incident, Nina feels happy about the small bit of shining she got to experience.

The mayor of Anima City, Barbaray Rose, approaches Shirou about stopping bombers from attacking the city's medical center. Feeling the center could help cure her alleged disease, Michiru reveals her condition to Barbaray and insists she aid. Although Michiru and Shirou stop a gang from sneaking into the center, an explosion still goes off, which Shirou deduces was caused by two of the doctors trying to eliminate evidence. One of the doctors tries to take Michiru hostage, but Shirou manages to save her.

As Shirou remains doubtful of Michiru's claims that she is a human, Michiru is told by Mary to meet with Gram Grandma in Rabbit Town to retrieve her stolen wallet. Michiru begins teaching orphan kids how to read and write, until Gram Grandma decides to sell them all off to pay off a debt to a gang. While attempting to escape with the children in tow, Michiru becomes able to change the size of her arms to free herself. After Gram Grandma is arrested, Michiru becomes upset with Shirou for not intervening sooner, proving with her student ID that she was human.

In a world where both humans and beastkin exist, a tanuki beastkin named Michiru Kagemori travels to the beastkin-dedicated city, Anima City, with help from shady mink beastkin Mary Itami. Upon arriving in the city, which is holding a festival celebrating its tenth anniversary, Michiru's wallet is stolen. While trying to track down the thief, Michiru is caught up in a bombing, where she is saved by a wolf beastkin named Shirou Ogami. Discovering that the bomb was planted by beastkin mercenaries paid by anti-beastkin humans to sabotage the festival, Shirou violently beats up the attackers before he is stopped by Michiru, who reveals she used to be human.