Though he wants nothing to do with his family's paranormal investigation business, a Stanford junior pairs up with his estranged brother on a road trip from the Bay Area to Los Angeles when their father goes missing. Along the way, they encounter mysterious people and situations from American myths and legends.
First Aired: 2008-11-13 Sam and Dean must team up with Ruby to find Anna, a girl who can listen in on angelic conversations... and who the demons want to acquire. Meanwhile, Sam fills Dean in on how he met Ruby during Dean's time in Hell.
First Aired: 2008-10-30 Castiel and his fellow angel, Uriel, tell the Winchesters to avoid interference with three creatures that are attacking a small town.
First Aired: 2008-10-23 Several men die from fright after being infected with a mysterious illness that causes acute anxiety, which leads to total terror. Sam and Dean investigate, and Dean becomes infected. Sam desperately searches for a cure before Dean dies.
First Aired: 2008-10-16 Sam and Dean look into a string of murders committed at Oktoberfest. The first victim is found with bite marks, leading them to believe they were caused by vampires. However, the second victim appears to be killed by a werewolf. When a mummy rises from the crypt, Dean believes that a shape-shifting demon is behind the attacks.
First Aired: 2008-10-09 Sam and Dean learn Jack Montgomery is transforming into Rugaru, a flesh-eating monster. People infected are unaware as to what is going on until they turn into cannibals and begin to eat human beings. Sam tries to reason with Jack so that he will control his urges, but Dean refuses to believe that the urges can be subdued.
First Aired: 2008-10-02 Dean is shocked to discover he has been transported back in time to Lawrence, Kansas. But the shock is short-lived after running into a younger John Winchester and Mary who are in love.
Dean is unaware why he was sent back but is enjoying his time with his parents and new-found grandfather, who may be the key to Sam and Dean's predicament.
First Aired: 2008-09-25 Sam and Dean are thrown off guard when the spirits of Meg and Agent Henricksen accuse the brothers of failing them. Though stunned, the brothers must help Bobby, who is devastated after fighting angry ghosts of children he couldn't save.
First Aired: 2008-09-18 Four months have passed and Dean awakes to find himself in a pine box -- he's been freed from Hell. He reunites with Sam and Bobby, but soon they all begin to wonder what pulled Dean out of Hell.
First Aired: 2008-05-15 It's 30 hours before Dean's deal with the crossroads demon is up and Dean, Sam and Bobby are searching for Lilith, who holds the contract. They discover her location and Sam summons Ruby for help despite Dean's protests. Ruby warns them they aren't ready to fight Lilith yet but they steal her knife and depart for New Harmony, Indiana. In a battle to the death, Sam, Dean and Bobby take on Lilith and all her demons in a last ditch effort to save Dean's life.
First Aired: 2008-05-08 The guys go after a doctor who has discovered the secret of maintaining his life as long as he takes other people's organ. Meanwhile, Dean goes to confront Bela and recover the Colt.
First Aired: 2008-04-24 Sam and Dean end up appearing on Ghostfacers, a reality TV show created by ghost hunters Ed Zeddmore and Harry Spengler. They all find themselves at the Morton Mansion where every year someone mysteriously disappears never to be seen again. Now the brothers must protect the Ghostfacers and defeat the ghost.
First Aired: 2008-02-21 Sam and Dean break into Bela's apartment to find the Colt, but Agent Henricksen is on the scene and arrests them both on the spot. While Sam and Dean are locked up in a jail in Colorado, a demon breaks in, kills the police, and possesses Henricksen. After the brothers do away with the demon, the FBI release release them, only to learn from Ruby that the jailhouse is surrounded by demons who want Sam dead.
First Aired: 2008-02-14 While investigating the disappearance of a missing man, Sam and Dean have to break in to the place where he disappeared, but they get caught, and Dean is shot and killed by the owner. When Sam wakes up the next morning he is shocked, Dean is alive, but as the day continues Sam realizes that they are re-living the previous day so he tries to stop Dean from getting shot, but he fails and Dean dies again... and again... and again, so Sam has to learn how to continue on without his brother.
First Aired: 2008-02-07 Dean, Sam and Bobby are forced to confront their internal demons when they go up against a killer who can trap and kill people in their dreams.
First Aired: 2007-12-13 It's Christmas and Sam and Dean look into the murders of people who were pulled through their chimney. While investigating, Sam learns that they are dealing with an Anti-Santa, a demon that has roots in pagan lore. When Dean wants to have an old-fashioned Christmas, Sam has flashbacks to a Christmas where he waited for his father to come home with one special gift.
First Aired: 2007-11-15 Sam and Dean capture Lucy, a female vampire, who has no knowledge of how she became a vampire. The brothers come across Dixon, a male vampire, who gives blood to females he meets in bars, telling them it's the "hottest new drug." Meanwhile, after escaping from prison, Gordon sets out to find Sam, but when Dixon intercepts him and turns him into a vampire, Gordon is now an even bigger threat to Sam.
First Aired: 2007-11-08 Sam and Dean investigate a series of drowning victims who were nowhere near the water at their time of death, but saw a ghost ship just before they died. During the investigation, they cross paths with Bela, who is being paid to solve the case by the family of one of the victims.
First Aired: 2007-11-01 A girl whom is trapped in a coma by her wicked stepmother starts a chain of murders based on fairy tales her father reads her. Meanwhile Sam tries to get Dean out of his deal.
First Aired: 2007-10-25 Sam and Dean investigate a group of violent deaths in Elizabethville, Ohio, a town that has quickly become home to many gamblers and drinkers. The execution of each death seems to follow a particular pattern of steps. Dean finds that demons have infiltrated the town and are using persuasive powers to help the townspeople succumb to basic human instinct. Ruby and Bobby rebuild the Colt, and Ruby delivers shocking news.
First Aired: 2007-10-18 Sam and Dean receive a call on their father's cell phone telling them that someone has broken into John's storage room in New York. There, they find that a cursed rabbit's foot has been stolen and call their old friend Bobby for help. Bobby tells them that whoever has touched the foot will have good luck until they lose the foot, which will result in the person dying. Since Sam has touch the foot, Dean buys lottery tickets, but when a thief steals it, Sam's life is in danger.