Kemonozume is about the story of a race of monsters known as the Shokujinki, who are cannibals. It's up to the Kifuuken, who are an elite team of beast hunters, to destroy them before it's too late. The story focuses on a young man named Toshihiko Momota, who is not only a professional swordsman, but he is also the son of the team's organization leader. One day, he falls in love with a beautiful young girl named Yuka. Unfortunately, their relationship becomes quite a difficult task, since Yuka is one of the Shokujinki.